James Page, Harry Cross, Piers Morel, Reece Beddows and Reece Chapman-Carry also come into the side for the clash with the Sharks.
Warriors Academy scrum-half George de Cothi, who made his first-team debut earlier this season against Leicester Tigers in the LV= Cup, and academy and England Under 18 back-row Andrew Boyce, will also be in action for the youngsters when they take on Sale.
Huw Taylor (captain), Jon Hughes, Callum Young and Andrew Kitchener, who have all represented Worcester Cavaliers in Aviva A League action this season, are expected to feature in the match in Greater Manchester.
Warriors team from:
Huw Taylor (C)
George de Cothi