Three changes on the bench see a call-up for former England scrum half Paul Hodgson, who could make his first appearance of the season after a summer move from London Irish.
Fiji international Ravai Fatiaki, this week named in the touring party for his country next month alongside team-mate Josh Matavesi, is also among the replacements.
Back row Blair Cowan is also set for a first taste of league rugby this season. The former Cornish Pirates man is among the replacements with Semisi Taulava ruled out through injury.
Head Coach Hill has called for his team to play with confidence and is keen for a strong start at Adams Park.
"We've done exceptionally well to score four tries at Northampton and against London Irish, but Wasps will pose a different threat away from home so we must not get too carried away," he said.
"We need to keep our feet on the ground. We've been working exceptionally hard and have prepared meticulously to attack and defend against Wasps. The players are hungry and ready to take Wasps on.
"If we had to criticise ourselves this season, it would be our inability to start strongly. Most of the games we've played we haven't started well," he added.
"We are finishing strongly and scoring more points than the vast majority of teams in the league, but in the first quarter we are not so strong. So away from home in particular, we will concentrate on starting well.
"The players have got to believe we can go down there and get a win. It will be tough, Wasps are a good side. But the confidence is sky high so there's no reason we can't put in a good performance."
Warriors vs. London Wasps
15 Chris Pennell
14 Jon Clarke
13 Alex Grove
12 Josh Matavesi
11 David Lemi
10 Andy Goode
9 Jonny Arr
1 Matt Mullan
2 Aleki Lutui
3 John Andress
4 James Percival
5 Dean Schofield (c)
6 Chris Jones
7 Sam Betty
8 Matt Kvesic
Replacements
16 Ollie Hayes
17 Ceri Jones
18 James Currie
19 Craig Gillies
20 Blair Cowan
21 Paul Hodgson
22 Joe Carlisle
23 Ravai Fatiaki




