He said: "We've drawn a line under last weekend and we will fight like mad against Quins.
"We will try and get the group in the right space as much as we can because there are too many good people here not to make sure they get every chance of fighting against relegation."
The former Gloucester boss believes Warriors have played some of their finest rugby against the country's elite this season and he is hoping they can do the same again this weekend.
He explains: "Ironically we have performed well against some of the top sides like Saracens, Northampton and Leicester.
"Quins are another great side so hopefully we can turn in an emotional performance like we did against Leicester."
Although Warriors are 12 points adrift of Newcastle Falcons in their Aviva Premiership relegation scrap, Ryan still believes his side are good enough to stay up.
He added: "Realistically, I think we can stay in the Premiership. I honestly believe we can.
"If we can perform emotionally like we did against Leicester and Northampton, then we can cause an upset.
"And if we can get a win, things will suddenly look a bit different."