Tom Wood will be skipper for the tough clash as part of a side crammed full of young talent. An exciting back division includes Simon Whatling and Uche Oduoza.
Ospreys - who are playing their second ever A match - are set to include young Welsh star Matthew Jones as the fly-half returns from a serious knee injury.
"For some of the players it will be a journey into the unknown," said Warriors Academy Assistant Manager Gary Meechan.
"To play against any Welsh side is always going to be a physical and mental encounter of which we relish as coaches in terms of the development of the players.
"We are looking forward to seeing Carl Robinson back. Depending on how the game goes we would like to give him game time and the chance to get some rugby back into his limbs."
Team: 01 Callum Black, 02 Matt Mullan, 03 James Tideswell, 04 Sam McDonald, 05 Tom Wood (c), 06 Dave Hughes, 07 James Collins, 08 Craig Everett, 09 Will Runciman, 10 Joe Carlisle, 11 Charlie Fellows, 12 Simon Whatling, 13 Alex Grove, 14 Uche Oduoza, 15 Jamie Lennard
Replacements: Matt Deacon, Jordan Page, Paula Havea, Rob Wood, Greg Evans, Tim Streather, Vince Lanciano, Carl Robinson
Ospreys: Matthew Jones, Martin Roberts, Richard Hibbard, Tal Selley, Richard Mustoe, Craig Mitchell, Ed Shirvington, Marc Breeze, Robert Lewis, Tom Smith, Michael Collins, Ben Lewis, David Blyth, Andrew Fisher, Jamie Davies, Ricky Williams, Lee Gadd, Nicky Thomas, Nicky Bevan, David Watts, Darren Ryan, N White, Chris Shelmerdine