Matt Powell returns at scrum half after missing the Tigers test because of suspension and Tom Harding comes in for the injured Drew Hickey at openside, with captain Pat Sanderson switching to blindside.
South African Thinus Delport starts on the wing, after Marcel Garvey was ruled out with a fractured eye socket, and Lee Best replaces the ruled out Shane Drahm at full back.
Phil Murphy returns on the replacements bench and is joined by Simon Whatling and Gavin Quinnell.
Worcester Warriors team to face Gloucester:
01 Tony Windo, 02 Chris Fortey, 03 Tevita Taumoepeau, 04 Craig Gillies, 05 Tim Collier, 06 Pat Sanderson (c), 07 Tom Harding, 08 Kai Horstmann, 09 Matt Powell, 10 James Brown, 11 Thinus Delport, 12 Gary Trueman, 13 Dale Rasmussen, 14 Aisea Havili, 15 Lee Best
Replacements: 16 Darren Morris, 17 Aleki Lutui, 18 Phil Murphy, 19 Gavin Quinnell, 20 Nick Runciman, 21 Simon Whatling, 22 Mark Tucker