However, with the incentive of putting more clear water between Warriors and the chasing pack, Horstmann is keen to talk team defence and not personal triumph on the eve of the encounter.
"It's an exciting milestone to notch up for your club, but that is not the most important thing to me or Pat on Saturday," said the Worcester skipper. "First and foremost, it's about putting Bedford away and getting a big result.
"Bedford are second in the table and pose a big threat, they also come to us on the back of losing down at Cornish Pirates so they will be itching to put things right.
"They will be up for it and it is a big challenge for us, but we have got to build on what we did at Bristol and certainly how we finished the game. We just need to address how we started.
"The defence will have to be huge for us on Saturday. It is always easy to attack when the defence is not putting much pressure on you so our aim will be to put as much pressure on Bedford as we possibly can and stop them from playing."
Horstmann has teamed up with Sanderson and combative flanker Neil Best in recent league games and acknowledges the trio are getting better as they become used to playing alongside each other.
But he revealed the race for a starting shirt means they cannot drop their standards as Warriors go hunting more league points.
"Pat is playing some very good rugby at the moment - and losing a lot of hair at the same time," laughed Horstmann. "But seriously, we have played a lot of rugby together at Warriors so it is a nice thing for us to get the 150 at the same time.
"He will be excited that he has got the milestone as well. But knowing Pat, like I do, his focus and mind come kick-off will purely be on the game and not how many games he has notched up., it won't enter his head.
"There is still plenty of pressure in the back row for places. Matt Kvesic is going well and Balders (Adam Balding), JC (James Collins) and also Jake (Abbott), when he is back fit, all want a spot. We have a wealth of talent there.
"We have been lucky as a current three that we have played quite a lot together and are developing a good relationship and understanding of how each other play. I certainly feel settled amongst Pat and Besty and we now need to keep pushing on and get even better."
Watch Pat Sanderson and Kai Horstmann hit the 150 milestone for Warriors. Call the Warriors Box Office today on 01905 454183 or click HERE for more information.