Worcester's preparations have been dealt a blow this week with the news that fly half Matthew Jones and full back Chris Latham will both miss the trip to the capital after suffering injuries.
Director of Rugby Ruddock remains confident his team can make it a hat-trick of top-flight wins but knows his new-look team will face a stern test against a Saracens side that are set to welcome back some star names.
"It would be nice if we could get a win but we expect it to be tough. Saracens have lost their last couple of games and so we expect a pretty severe backlash on their home soil," he said.
"But our goal is to put in a big performance and if we do that and play well then we could get a win. That is our aim but it will take a massive performance and our preparation has got to be right.
"This week has gone to plan, the boys have trained well and the feeling in game after a couple of wins is great. Now we need to use that spirit with good tactics to get a result.
"They have got some internationals back, they have had some big players missing and people that provide great leadership quality," he added.
"It will be tougher for us as we have lost a couple of our more significant players in Matt Jones and Chris Latham this week.
"That tips the scales in their favour and we will go as underdogs, but that suits us and I'm sure the boys will give a very good account of themselves."