Director of Rugby Ruddock admits Tuitupou will be missed throughout the rest of the season - on and off the field - but has backed fit again Wales international Luscombe to now move up a gear and show his class.
"Hal is back fully fit now and this will provide an opportunity for him to get back into action," said Ruddock.
"Hal is a class player and I've watched him train and he is running much better than before and looks more and more confident with his progress.
"He is experienced and skilful and if ever you are going to look for a player to step in and fill the gap of Sammy then I think Hal is the sort of guy you want.
"Hal is an international player who, don't forget, has played in a Grand Slam winning team. He has also played for a good Harlequins team over the last few years, he is a class act.
"On top of that we also have some good youngsters coming through with Alex Grove, who has already had some first team action, and Greg King."
Meanwhile, Ruddock has revealed the groundstaff at Warriors are working around the clock to enure the clash with Sale Sharks goes ahead despite wintery weather in Worcester.
"I know the club are going to do everything they can to get the game on despite the fact that the weather is very cold at the moment," he added.
"The club are looking at options with covering and heating to try and make sure the pitch is not frozen."